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pCBRG-MEF2 RE

CBV20036

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Introduction
Description: pMEF2 RE-Luc is designed for monitoring the induction of The myocyte enhancer factor 2 .MEF2 transcription factor acts as a lynchpin in the transcriptional circuits that control cell differentiation and organogenesis. The spectrum of genes activated by MEF2 in different cell types depends on extracellular signaling and on co-factor interactions that modulate MEF2 activity. Recent studies have revealed MEF2 to form an intimate partnership with class IIa histone deacetylases, which together function as a point of convergence of multiple epigenetic regulatory mechanisms. We review the myriad roles of MEF2 in development and the mechanisms through which it couples developmental, physiological and pathological signals with programs of cell-specific transcription.
Plasmid profile:
Unit Size: 1-4μg
Pathway (Activitor): MEF2
Pathway profile:
Full Name: Myocyte enhancer factor-2
Cis response element: MEF2 RE
Shelf Life: One year from date of receipt under proper storage conditions.
Storage: -20°C
Mode of transportation: Ice bag transport
Matters needing attention: For your health, please wear lab clothes and disposable gloves.

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