SDC4-ROS1/BaF3
CBP73320
詢(xún) 價(jià)
留 言
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
| I. Introduction | |
|
Cell Line Name： |
SDC4-ROS1/BaF3 |
|
Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
|
Application: |
Anti-proliferation assay and PD assay |
|
Freeze Medium: |
90% FBS+10% DMSO |
|
Complete Culture Medium: |
RPMI-1640+10%FBS |
|
Mycoplasma Status: |
Negative |
| II. Background | |
| SDC4, syndecan 4, is a heparan sulfate proteoglycan that plays a role in intracellular signaling, including cell adhesion and cell-matrix interactions. SDC4 expression has been associated with breast cancer, a SDC4-ROS1 fusion has been identified in NSCLC and a SDC4-NRG1 fusion has been identified in lung adenocarcinoma and squamous cell carcinoma . | |
| III. Representative Data | |
|
1. Sanger of SDC4-ROS1/BaF3
|
|
|
2. Anti-proliferation assay
Figure 2. CTG Proliferation Assay of BaF3 SDC4-ROS1 (C1). |
|
