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CARD11 p.R555Gfs*45 Reference Standard

CBP10742

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Introduction 
Format Genomic DNA
Description CARD11, caspase recruitment domain family, member 11, is a component of a scaffold complex that regulates NFKB activity . Activating mutations in the CARD11 coiled-coil domain activate NFKB and have been identified in hematological cancers, including diffuse large B cell lymphoma and may confer resistance to ibrutinib.
   
Technical Data 
DNA Change c.1663del
AA Change p.R555Gfs*45
Mutation type Deletion - Frameshift
Zygosity Heterozygous
Allelic Frequency 65.21%(DdPCR)
Transcript ENST00000396946.4
Cosmic ID COSM1450247
Chr position(GRCh37) chr7:2968329
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA 
Storage 2-8
Expiry 36 months from the date of manufacture

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藥靶模型聯(lián)系方式: 華東銷售經(jīng)理(上海):18240630236 華東銷售經(jīng)理(上海、江蘇、安徽):15715191010 華北銷售經(jīng)理:18628311252 華南銷售經(jīng)理:13823536064 華中&華西銷售經(jīng)理:18071545918 華中&西南銷售經(jīng)理:13871580511 全國銷售經(jīng)理:13816461235
診斷標(biāo)準(zhǔn)品聯(lián)系方式: 華東銷售經(jīng)理:15000320447 華北銷售經(jīng)理:18628311252 華南銷售經(jīng)理:13823536064 華中&華西銷售經(jīng)理:18071545918 華中&西南銷售經(jīng)理:13871580511 全國銷售經(jīng)理:13816461235

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