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PIK3CA p.E726K Reference Standard

CBP10112

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Introduction 
Format Genomic DNA
Description PIK3CA E726K does not lie within any known functional domains of the Pik3ca protein (UniProt.org). E726K has not been biochemically characterized, but is predicted to confer a gain of function on the Pik3ca protein as demonstrated by increased transFormation in cell culture (PMID: 29533785).
   
Technical Data 
DNA Change: c.2176G>A
AA Change p.E726K
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000263967
Cosmic ID COSM87306
Chr position(GRCh37) chr3:178938934
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8
Expiry 36 months from the date of manufacture

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